A first-look at the documentary on Ed Sheeran’s life shows the emotional moment he breaks down in tears while opening up about his wife Cherry Seaborn’s health struggles.
Earlier this month, the singer took to Instagram to share the news that Seaborn, who he’s been married to since 2019, was diagnosed with a tumour while pregnant with their second child last year.
Within the same month, the singer’s best friend, Jamal Edwards, tragically passed away.
These difficult life events changed the course of Sheeran’s upcoming Disney+ docu-series The Sum of It All, something that he discusses in the trailer.
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“Cherry’s health, it was really bad, and then suddenly my best friend Jamal dies,” he explains.
“You guys said, ‘Do you want to make a documentary?’ And I went, ‘Yeah, it should be me in the studio and we’ll play the gig.’
“That’s not what the documentary is.”
The camera then cuts to the ‘Shape of You’ singer in a car as he bursts into tears.
And hundreds of people have offered words of support, with one writing in the trailer’s YouTube comments: “This doc series just proves that even when fans thinks he’s a super figure… he’s just a human with ups and downs just like the rest of us.
“So much respect for Ed and Cherry!”
Another wrote: “I’m so excited for this, he deserves every bit of success and good things in his life.
“You can always see the passion he has for music and expressing himself, that has never changed.”
“Real life comes to all of us, no matter where we’re at,” added a third. “I’m hoping you Cherry and the girls are doing well.”
The upcoming documentary, which also coincides with Sheeran’s sixth studio album release ‘Subtract’, is said to take viewers on a journey into how an ‘unlikely child with a stutter rose to fame to become one of the biggest global music superstars’.
Per the official synopsis: “For the first time, global superstar Ed Sheeran opens the doors to a definitive and searingly honest view into his private life as he explores the universal themes that inspire his music.
“This series follows Ed after he learns of life-changing news and reveals his hardships and triumphs during the most challenging period of his life.”
Scientists Discover the Reason Humans Lost Their Tails
One of the most remarkable changes in human evolution is the loss of our tails, a transformation that occurred around 25 million years ago. This pivotal shift not only altered the trajectory of our species but also marked a significant moment in the evolutionary history of primates. While scientists have long speculated on why humans lost their tails, the genetic cause has remained elusive—until now. A recent study published in Nature has finally uncovered the genetic factors responsible for this evolutionary change.
The Quest to Understand Tail Loss
The journey to unravel the mystery of human tail loss began in an unexpected way. Bo Xia, a graduate student at New York University, was inspired to investigate the origins of the human tailbone after injuring his own coccyx. This personal curiosity led Xia and his team to embark on a groundbreaking scientific investigation.
Through careful research, the team focused on the TBXT gene, which plays a crucial role in regulating tail length in various species. Their research revealed a unique genetic mutation within this gene, providing a major breakthrough in understanding human evolution.
The Role of Jumping Genes
A key aspect of this discovery lies in the role of Alu elements, often called “jumping genes.” These genetic elements, specific to primates, can move within the genome and cause significant changes. The researchers found that Alu elements inserted themselves into the TBXT gene, triggering a chain reaction that led to the loss of our tails.
This insertion activated a process known as alternative splicing, where RNA molecules are cut and restructured, which ultimately led to the deletion of a crucial exon. This change altered the structure and function of the resulting protein, leading to the tail loss seen in humans.
Validation Through Mice Studies
To confirm their findings, the researchers engineered laboratory mice with the same genetic mutations found in humans and apes. These genetically altered mice lost their tails, providing compelling evidence that the identified mutation plays a crucial role in the absence of tails in humans and other primates.
However, the study also uncovered a downside to tail loss: an increased risk of neural tube defects, such as spina bifida. This finding highlights the complex balance between evolutionary benefits and potential genetic trade-offs.
The Broader Implications
This discovery has profound implications not just for understanding human evolution, but also for human anatomy and health. The loss of our tails was not a random event but a genetic adaptation with lasting consequences. It illustrates the complex relationship between genetic changes and the way they shape our physiology over time.
As we continue to study our evolutionary past, these findings remind us of the intricate process of natural selection and genetic innovation that has shaped humanity. This breakthrough also underscores the power of scientific inquiry in uncovering the mysteries of our origins, offering insight into the past that can help us understand our future.
The identification of the genetic reasons behind tail loss is a testament to the persistence of scientific exploration and the ongoing quest for knowledge about our evolutionary journey.
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