Within the realm of retro beauty accessories, the lipstick case is a notable representation of glitz, sophistication, and individual flair. Vintage lipstick cases were made to be more than simply a place to store lipstick; they were works of art that could be found in any woman’s handbag, a far cry from the disposable, frequently simple packaging of today’s cosmetics. These cases, which date from the early 20th century to the mid-20th century, are highly sought-after objects for collectors and lovers of vintage beauty products because they capture the style, materials, and craftsmanship of their eras.
Vintage lipstick cases were a reflection of the artistic sensibilities of their day, made from a range of materials such as brass, gold plating, enamel, semi-precious stones, and exquisite etchings or inlays. Cases with geometric designs, crisp lines, and opulent metallic embellishments were popular in the 1920s and 1930s, reflecting the Art Deco trend. A return to femininity and luxury was witnessed throughout the post-war era, as cases grew more elaborate and included romantic designs, like as flowers and birds, which were frequently inlaid with pearls or colored stones.
These enclosures were technical and functional miracles in addition to being stunning. Many included an integrated mirror that made it possible to apply lipstick while on the go, and some even had a little space for powder or a miniature perfume bottle, which embodied the era’s requirement for small, efficient accessories. These jewels were masterfully crafted; designers such as Cartier, Van Cleef & Arpels, and Tiffany & Co. created pieces that served as status symbols in addition to being useful.
Vintage lipstick cases are nostalgic and provide insight into the everyday routines and particular preferences of ladies from the past. They take us back to a bygone era when beauty routines were infused with a feeling of elegance and formality, which contrasts sharply with the modern emphasis on efficiency and speed. Many people have developed a passion for collecting these items because of their artistry and beauty as well as the histories and tales they represent.
Vintage lipstick cases require careful cleaning and periodic polishing (for metal cases only) to keep them shiny and free of tarnish. The excitement of the chase is part of the fascination of searching for these gems, which can lead aficionados to antique stores, estate sales, and online auctions. A vintage lipstick case is more than simply a container, whether it’s on show on a vanity or tucked away in a purse; it’s a tiny piece of history and a relic of a bygone era’s devotion to elegance and beauty.
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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